Tuesday, April 23, 2024

Does Acyclovir Help Genital Herpes

Understanding Herpes With H Hunter Handsfield Md

Acyclovir for herpes viral infections

Herpes expert H. Hunter Handsfield, MD, explains the basics about genital herpes, including the difference between genital HSV-1 and HSV-2 infection, testing options and the importance of knowing virus type, and the three-prong strategy for prevention. See more herpes videos at sexualhealthTV.com.

Have a question about herpes youd like Dr. Handsfield or our other experts to answer? Visit our Ask the Experts page to learn how.

How To Use Rhubarb And Sage Cream On A Cold Sore

Apply a cream combining rhubarb and sage directly to lesions three to four times a day.

Topical zinc oxide cream may shorten the duration of cold sores.

In a , cold sores treated with zinc oxide went away, on average, 1 1/2 days sooner than those treated with placebo. Zinc oxide also reduced blistering, soreness, itching, and tingling.

What Are The Types Of Herpes Viruses

Herpes is a group of contagious viruses that cause blisters and sores. Some of the more common herpes viruses include:

  • Type 1: HSV-1, or oral herpes, causes cold sores to form on your lips, gums, tongue and inside of your mouth. It can cause genital herpes in some cases. This type usually spreads through saliva when you kiss someone with open herpes sores. You can also get HSV-1 by sharing items like toothbrushes, lipsticks or eating utensils.
  • Type 2: HSV-2 causes genital herpes.
  • Herpes zoster: This virus causes chickenpox and shingles.

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When Is Preventive Treatment Considered

Some people have outbreaks of genital herpes very often or experience especially severe symptoms. Then it may be a good idea to take antiviral medication for a longer time including during symptom-free phases. The goal is to prevent further outbreaks and to keep the symptoms from becoming so severe. Also, the antiviral medication reduces the likelihood of infecting others. As preventive treatment, the WHO recommends the following:

  • aciclovir: 400 mg two times per day,
  • famciclovir: 250 mg two times per day or
  • valaciclovir: 500 mg once per day.

Research shows that preventive treatment can considerably lower the risk of further outbreaks. The people participating had four or more herpes outbreaks per year before the start of the studies, and then took an antiviral medication or a fake treatment for up to one year. A comprehensive analysis of the study results shows that

  • 96 out of 100 people who took a placebo had at least one further outbreak of genital herpes.
  • 46 out of 100 people who were given antiviral medication had at least one further outbreak of genital herpes.

In other words, the medication prevented further outbreaks in 50 out of 100 people within one year.

People with very frequent herpes outbreaks also benefited from preventive treatment: In one study involving people with very frequent outbreaks, the medication lowered the number of episodes in one year from 11 to 2.

What Happens If You Leave Herpes Untreated

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According to the CDC , genital herpes can lead to painful sores, which can be worse in people with weaker immune systems. A person may also spread the virus to other parts of their body.

In pregnant people, herpes may lead to miscarriage or make early delivery more likely. A person can also pass herpes on to their baby before or during birth. This can cause neonatal herpes, which can be fatal.

Pregnant people with herpes may need to receive herpes treatment toward the end of their pregnancy and have a cesarean delivery if they have herpes symptoms when they give birth.

It is important that people speak with a doctor about treating herpes.

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Valacyclovir For First Herpes Outbreaks

For first-time herpes outbreaks, valacyclovir is most effective when its used within 48 hours of symptoms appearing. Once valacyclovir has converted into acyclovir, it has a half-life of 2.5 to 3.3 hours in people with normal renal function. Meaning Valacyclovir stay in your system from 2.5 to 3.3 hours for normal people.

The standard dosage of valacyclovir for first-time herpes outbreaks is 1,000 mg two times per day over a period of 10 days. Valacyclovir usually starts treating herpes symptoms as soon as its in your system, but can take several days to produce a noticeable improvement.

It can take up to 10 days for herpes blisters to heal even with valacyclovir treatment. This makes it important to start treatment as soon as you notice herpes symptoms.

In some cases, your doctor might prescribe valacyclovir for a longer period than 10 days or at a different dosage. In this case, follow your doctors instructions and make sure you complete the full course of the medication, even if the herpes blisters heal before the end of the period.

What Should I Discuss With My Healthcare Provider Before Taking Acyclovir

You should not take this medicine if you are allergic to acyclovir or valacyclovir . You should not take acyclovir buccal tablets if you are allergic to milk proteins.

Tell your doctor if you have ever had:

  • kidney disease or
  • a weak immune system .

Tell your doctor if you are pregnant or breastfeeding.

Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Acyclovir should not be given to a child younger than 2 years old.

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Can You Get Shingles More Than Once

Plus, why its important to get the shingles vaccineeven if youve had shingles before.

Its tough enough to endure shingles once in your life. After all, its painful to experience the red blister-like bumps that are characteristic of shingles, caused by a reactivation of the varicella zoster virus .

You probably already know its really rare to get chickenpox twice. But is it possible to get shingleswhich can feel intensely painful, like a burning, stabbing sensation and can last for two to six weeksmore than once?

Unfortunately, it is possible to get shingles twice . In fact, of the one in three people who experience shingles, women are at a higher risk of developing it a second time than men are. The longer you experience severe pain after shingles , the higher your chances of a shingles recurrence.

Interestingly, if shingles comes back, it may recur on another side of your body. If the rash first appeared on the left side of your torso, for example, its likely to come back on the right side, Nidhi Ghildayal, PhD, an infectious disease specialist and researcher at the University of Minnesota School of Public Health in Minneapolis, tells Health.

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How To Use Epsom Salt For Herpes A Complete Beginners Guide

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  • Epsom Salt is a chemical compound made up of three elements, i.e., magnesium, sulfur, and oxygen.
  • Epsom salt captures the goodness of Magnesium, which is universally known as an analgesic agent.
  • Epsom salt also helps in regulating metabolic conditions such as diabetes and hypertension.

Using Epsom salt for the first time could be a daunting task if you are a newbie in the business. Most of our brothers dont know the right approach to using this mineral to render this naturally occurring minerals health benefits altogether.

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Rule #: Dont Touch It

Touching the sores can increase the chance that you spread the virus to other parts of your body or to other people. Make sure to wash your hands frequently. Also, you can use a cotton swab or a finger cot to apply cream or ointment to the affected area instead of your fingers to avoid spreading the virus to other regions .

This Time It Was Shingles Lovely But At Least Then I Could Figure This One Out For You Too: The Best Natural Remedies For Shingles That Work

Yep, thats my back in the picture above, you even get a peek at my owl pajamas, ha! I had shingles a few months ago and Im just now finding the time to tell you about it. Ill share some of what I wrote in my daily notes to keep track of what was happening.

It began as quite the mystery nothing was making sense at first

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What Are Recurrences Of Herpes And How Likely Are They

Recurrences are repeat symptoms which appear at or close to the place where the infection was first noticed in the same dermatome . These are often fairly minor and may be no more than a small spot that heals in a few days. They may be accompanied by sensations itches or nerve twinges. They are unlikely to be as severe as first symptoms and may be almost unnoticed.

Who Gets Genital Herpes

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Any sexually active person can get genital herpes. Its very common. According to the Centers for Disease Control , about 1 in 6 people in the United States who are 14 to 49 years old has genital herpes.

Many people who have genital herpes dont know it because they never develop symptoms. This makes genital herpes easy to spread.

While its easy to get infected, some people have a higher risk of getting genital herpes. Women are more likely to get infected during sex. People who have many sexual partners also have a higher risk.

Anyone who has a weakened immune system also has a higher risk. People can have a weakened immune system for many reasons. Medication is one reason. Medications that weaken the immune system include those taken to prevent losing a transplanted organ and some that control severe psoriasis.

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What Should I Know About Storage And Disposal Of This Medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture .

It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location â one that is up and away and out of their sight and reach.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.

Treatment For Oral Herpes

The antiviral medications available in pill form have been specifically developed for the treatment of genital herpes. However, it is not uncommon for healthcare providers to prescribe the antiviral drugs to those who have frequent or severe outbreaks of oral herpes.

A recent study found valacyclovir to be effective for treating oral herpes in a one-day treatment of 2 grams taken at the first sign of a cold sore, and then again about 12 hours later.

There are two topical antiviral medications prescribed for the treatment of oral HSV symptoms: acyclovir ointment and penciclovir cream. Both work to speed up the healing process and reduce the viral activity. These topical drugs are put directly on the lesions themselves, but can also be used at the onset of prodrome.

Other topical treatments for oral herpes are available over-the-counter , but are not antiviral compounds like acyclovir and penciclovir. Some also contain ingredients that numb the area and induce temporary relief from the discomfort of an outbreak. Unfortunately, some OTC treatments may actually delay the healing time of symptoms because they can further irritate the area with repeated applications. There is only one OTC FDA-approved cream, called Abreva®, which has been clinically proven to help speed the healing process.

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How Far Away Is A Cure For Herpes

Theres currently no cure for herpes, but that might change in the future.

According to 2020 research published in Nature, scientists from the Fred Hutchinson Cancer Research Center removed 90 percent of the HSV-1 virus from cells in mice using gene editing.

However, it takes time to transition potential treatments from animals to humans. In a 2020 news article, one of the researchers that authored the Nature paper estimated that it would be at least 3 years before human trials.

Scientists are also researching the possibility of creating a vaccine to prevent herpes. A 2022 study outlined a new approach to developing an mRNA vaccine for herpes. The vaccine mentioned in the study worked well in mice and guinea pigs.

The researchers say that theyre aiming to conduct human trials before the end of 2022, and the vaccine could be available within the next 10 years.

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Scientists have studied alternative treatments, like herbal extracts and nutritional supplements, based on some genital herpes patients’ claims that they help relieve symptoms. Some study results have been promising, others discouraging.

Many people say that an extract of the echinacea plant helps boost the immune system’s ability to fight the genital herpes infection. Some say it decreases the frequency and severity of genital herpes outbreaks. Researchers in the U.K. compared the effect of echinacea with that of a placebo. They gave echinacea to 50 people with genital herpes for six months and a placebo for another six months. There was no significant difference in the number of herpes outbreaks during the two periods.

Another study showed that an ointment containing propolis, a waxy substance that honeybees make, may help genital herpes sores heal. Sores healed faster for people using the propolis ointment than in those using ointments containing the antiviral drug acyclovir or a placebo. The ointment was applied to herpes sores four times a day. After 10 days, 24 of the 30 people using propolis ointment said their sores healed, compared with 14 of the 30 people using acyclovir ointment and 12 of the 30 using a placebo.

Researchers have also found that the herb Prunella vulgaris, and an edible mushroom, Rozites caperata , contain chemicals that fight both the oral herpes virus and the genital herpes virus .

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Types Of Antiviral Drugs

There are three oral antivirals recommended for the treatment of oral or genital herpes:

Famvir, 250 mg Twice daily

Preventing genital herpes recurrence is important as it reduces the risk of HIV. According to the CDC, having an active genital herpes infection increases the risk of HIV by 200% to 300%.

Other Triggers For Genital Herpes Outbreaks

Other triggers of genital herpes may include:

  • Sexual intercourse. Some people find that the friction of sexual intercourse irritates the skin and brings on symptoms. Using a water-based lubricant can help reduce irritation. Don’t use one that contains the spermicide nonoxynol-9, however. Nonoxynol-9 can irritate mucous membranes, such as the lining of the . Oil-based lubricants are a no-no, too. They weaken latex, making condoms more likely to break. Even if the friction of intercourse seems to be a trigger for symptoms, it probably won’t cause a flare-up every time you have sex.
  • Colds and sunlight. The common cold and sunlight seem to trigger outbreaks of oral herpes , but no proof exists that they trigger genital herpes outbreaks.
  • Hormones. Hormonal changes, like those that occur in the menstrual cycle, can affect genital herpes outbreaks. No one knows why.
  • Surgery, weak immune system. Trauma to the body, such as having surgery, may make herpes symptoms appear. It’s possible that having a weakened immune system does, too. People whose immune systems are weakened by HIV, for example, tend to have outbreaks more often than people with normal immune functioning.

Remember that triggers may not be the same for everyone, and doctors are not certain how much lifestyle affects outbreaks of herpes symptoms. If you think something in particular triggers symptoms, ask your doctor what you should do about it.

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How Should I Take Acyclovir

Take acyclovir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Start taking acyclovir as soon as possible after the first appearance of symptoms . Start taking Sitavig within 1 hour after you first notice sold core symptoms, before the cold sore appears.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Do not crush, chew, suck on, or swallow a buccal tablet. Place the flat side of the tablet against your upper gum, on the same side of the mouth as your cold sore. Allow the tablet to dissolve in your mouth throughout the day. You may eat and drink normally while the buccal tablet is in place.

Do not give an acyclovir buccal tablet to a young child or choking could occur.

Shake the oral suspension before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device .

Acyclovir doses are based on weight . Your dose needs may change if you gain or lose weight.

Drink plenty of water while you are taking this medicine to keep your kidneys working properly.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses may increase the risk of your virus becoming resistant to medication.

Store at room temperature away from moisture and heat.

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