Suppressive Therapy For Recurrent Hsv
Suppressive therapy reduces frequency of genital herpes recurrences by 70%80% among patients who have frequent recurrences . Persons receiving such therapy often report having experienced no symptomatic outbreaks. Suppressive therapy also is effective for patients with less frequent recurrences. Long-term safety and efficacy have been documented among patients receiving daily acyclovir, valacyclovir, and famciclovir . Quality of life is improved for many patients with frequent recurrences who receive suppressive therapy rather than episodic treatment . Providers should discuss with patients on an annual basis whether they want to continue suppressive therapy because frequency of genital HSV-2 recurrence diminishes over time for many persons. However, neither treatment discontinuation nor laboratory monitoring is necessary because adverse events and development of HSV antiviral resistance related to long-term antiviral use are uncommon.
Valacyclovir 500 mg orally 2 times/day for 3 daysOR
Valacyclovir 1 gm orally once daily for 5 days
*Acyclovir 400 mg orally 3 times/day is also effective, but are not recommended because of frequency of dosing.
Questions To Ask Your Doctor
- What is the best treatment for me?
- Are there any side effects to my treatment?
- Is it safe to have unprotected sex if I dont have any sores?
- Can I give myself genital herpes if I also have oral herpes?
- Can I give someone else herpes even if Im not having an outbreak?
- What is the best way to prevent herpes outbreaks?
- Can I live a normal life with herpes?
- Am I at risk of developing any other diseases?
- Are there any support groups in my area?
- If I give my baby herpes, what is the treatment?
Side Effects Of Acyclovir
The most common side effects of acyclovir are nausea and vomiting, but these only happen in about 23% of people .
Sometimes, acyclovir is prescribed as a long-term treatment of six months or longer, specifically for people who have recurrent ocular herpes simplex . With long-term use of acyclovir, nausea and vomiting are more prevalent, and headaches are a common side effect, too.
Also Check: Is There Any Treatment For Herpes
Warnings For People With Certain Health Conditions
For people with kidney problems: Your kidneys clear this drug from your body. If you have kidney problems or a history of kidney disease, you may not be able to clear it from your body. This may increase the levels of the drug in your body and cause more side effects. This drug can also make your kidney function worse. To help prevent these problems, your doctor may prescribe a lower dosage of this drug for you.
For people with advanced HIV or a history of transplant: If you have advanced HIV or a history of bone marrow or kidney transplant, you may be at a higher risk of certain blood disorders. These conditions are called thrombocytopenic purpura and hemolytic uremic syndrome . They can result in severely low red blood cells and platelets in your body. TTP or HUS can cause death.
Interactions With Other Drugs
Drug interactions happen when two or more drugs combine in the body and to create unintended effects or symptoms. Interactions can range from mild to severe and dangerous. See the chart below for some examples.
Valacyclovir can interact with over 60 different drugs, which is why it’s important to let your physician know about any medications you’re taking. For example, valacyclovir can cause serious negative interactions with several medications used to treat HIV, including:
Be sure to tell your physician if you have HIV and if you’re taking medications or taking treatment to control it.
Valacyclovir can also be dangerous when taken in combination with a class of drugs called aminoglycoside antibiotics. This includes drugs such as:
Aminoglycosides along with certain other antibiotics, like bacitracin and valacyclovir can potentially cause kidney damage, and this risk increases when the drugs are taken together.
This is not a full list of possible drug interactions. If you’re using any other medications, consult a more complete list of possible interactions and speak with your doctor and pharmacist for more information.
You May Like: How To Know If It’s Herpes
Are There Any Other Precautions Or Warnings For This Medication
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Genital herpes: To reduce the risk of spreading the virus, wash your hands immediately after touching your skin sores. You should avoid intimate contact when live lesions are visible on your skin. The herpes virus can still be spread even when you do not have blisters or sores.
Immunosuppression : People who have a weakened immune system should only use valacyclovir if the benefits outweigh the risks. If you have had an organ transplant, are infected with HIV, or otherwise have a weak immune system, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney disease: Valacyclovir may cause decreased kidney function or kidney failure. People with kidney disease may need a lower dose of this medication. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
It Might Be More Challenging To Find Partners
Hopefully this will become less true as more people become educated about genital herpes. But for now, having the facts about genital herpes can help you talk more openly with potential sexual partners.
Though it can be daunting and awkward, it’s important to disclose your genital herpes diagnosis to a new potential sexual partner. And sometimes learning more about the disease can help to lessen their fear.
For instance, one helpful study shows that if an infected person takes daily valacyclovir as a preventative, they have a less than 2% chance of spreading HSV-2 to a sexual partner.
Also Check: How Soon Does Herpes Develop
Prevention Of Genital Herpes
The best protection against STIs is to always use barrier protection such as condoms, female condoms and dams . Because herpes is spread by skin-to-skin contact, condoms will reduce the risk of transmission, but it will not protect sexual partners completely as condoms do not cover the entire genitals.
Using lubricant with a condom during sex will also reduce the risk of trauma to the genital skin. This has been shown to reduce HSV transmission, especially in the first six months of a sexual relationship. Silicone-based lubricants are recommended.
Remember that herpes transmission can occur when symptoms are present , but may also occur even if there are no genital symptoms through asymptomatic viral shedding.
For people who have frequent episodes of genital herpes, antiviral medication, taken daily, helps to reduce transmission of herpes to a sexual partner.
Also Check: Can Herpes Ever Go Away
Valacyclovir May Interact With Other Medications
An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help prevent interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking.
To find out how valacyclovir oral tablet might interact with something else youre taking, talk to your doctor or pharmacist.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that youre taking.
This drug comes with several warnings.
Recommended Reading: At Home Treatment For Genital Herpes
Over The Counter Genital Herpes Treatment Cream
Several types of over-the-counter genital herpes treatments are available on the market. While traditional treatments may provide a temporary cure, they dont often offer lasting relief. Topical treatments may not be the best choice if you want to prevent future outbreaks. In addition to topical treatments, DIY topical compresses are a good way to alleviate outbreaks. But there are also risks associated with using these creams.
Over-the-counter treatments are only effective if you can prevent future outbreaks. These treatments should be used as directed by your physician, and they are not a cure for the disease. They are designed to minimize the discomfort of outbreaks but do not cure them. While these over-the-counter treatments are not recommended for chronic outbreaks, they can effectively treat a cold sore or prevent an outbreak from developing.
Over-the-counter treatments can help you manage outbreaks while theyre forming. It would be best if you tried to limit your exposure to herpes-infected people and other affected areas. The goal is to reduce outbreaks and prevent the spread of herpes to as many people as possible. Luckily, there are many options for treating herpes, and there are also many things you can do at home to limit the spread of the disease.
What Side Effects Are Possible With This Medication
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- increased sensitivity to UV light
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- behaviour changes
- pain in the side between the ribs and hip or kidney area of the back
- signs of anemia caused by red blood cell destruction
- signs of bleeding
- signs of decreased kidney function
Stop taking the medication and seek immediate medical attention if any of the following occur:
- signs of a serious allergic reaction
- signs of a severe skin reaction
You May Like: Over The Counter Herpes Medication Cvs
Risk For Genital Herpes
According to the US Centers for Disease Control and Prevention , about 1 in 6 Americans ages 14 to 49 years have genital herpes. While HSV-2 remains the main cause of genital herpes, HSV-1 has significantly increased as a cause, most likely because of oral-genital sex. Except for people in monogamous relationships with uninfected partners, everyone who is sexually active is at risk for genital herpes.
Risk factors for genital herpes include:
- History of an STD
- First sexual intercourse at an early age
- High number of sexual partners
- Low socioeconomic status
Women are more susceptible to HSV-2 infection because herpes is more easily transmitted from men to women than from women to men. About 1 in 5 women, compared to 1 in 9 men, have genital herpes. African-American women are at particularly high risk.
People with compromised immune systems, such as those who have HIV, are at very high risk for genital herpes. These people are also at risk for more severe complications from herpes. Drugs that suppress the immune system, and organ transplantation, can also weaken the immune system and increase the risk for contracting genital herpes.
Talk With Your Doctor About Herpes Medications
Its important to first talk with your doctor before using over-the-counter products like docosanol or other home remedies.
If this is the first time you have symptoms of HSV with blisters or sores, your doctor will first diagnose if you have HSV, the type and discuss options to manage your condition. They will tell you about prescription and nonprescription alternatives to treat your HSV infection.
Tell your doctor if you have any serious health conditions including if you have a weakened immune system.
Your doctor will also tell you what you can expect with an HSV infection, how long it may last, and what do to prevent spreading HSV to others while you have an active infection.
Here are answers to a few commonly asked questions about herpes simplex virus.
Also Check: Can I Get Genital Herpes From Kissing
When Should I Call My Healthcare Provider
Treating herpes meningoencephalitis as soon as possible is essential. If youre feeling neck stiffness, having any neurological problems , are sensitive to light, or are running a fever along with a bad headache, call your healthcare provider and have the problem treated promptly.
If you have already been diagnosed with herpes meningoencephalitis and are being treated, its very important to let your healthcare providers know if any of your symptoms get worse or if you develop any new symptoms, as these could be signs that the infection is getting worse despite treatment.
Also Check: Does The Shingrix Vaccine Help With Herpes
How Does Herpes Simplex Spread
Herpes spreads through close contact with a person who has the infection. The virus can be found in skin and saliva. If you have herpes simplex, you are most likely to pass the virus to another person when you have sores. But you can infect someone else even if you have no symptoms. Healthcare providers call this asymptomatic viral shedding.
People may get HSV-1 through
- Touching a persons skin near the mouth.
- Sharing food utensils, lip balm or razors.
- If you receive oral sex from someone who has a cold sore, it may spread a herpes infection to your genitals.
People may get HSV-2 through
- Oral sex with someone whos infected.
- Touching open sores, including while breastfeeding.
- Childbirth by a mother or gestational parent who has an active infection.
You cant get genital herpes from objects like toilet seats. But you could pass genital herpes through shared sex toys.
You May Like: Antibodies For Herpes 1 And 2
Genital Herpes During Pregnancy
Prevention of neonatal herpes depends both on preventing acquisition of genital herpes during late pregnancy and avoiding exposure of the neonate to herpetic lesions and viral shedding during delivery. Mothers of newborns who acquire neonatal herpes often lack histories of clinically evident genital herpes . The risk for transmission to the neonate from an infected mother is high among women who acquire genital herpes near the time of delivery and low among women with prenatal histories of recurrent herpes or who acquire genital herpes during the first half of pregnancy . Women who acquire HSV in the second half of pregnancy should be managed in consultation with maternal-fetal medicine and infectious disease specialists.
All pregnant women should be asked whether they have a history of genital herpes or genital symptoms concerning for HSV infection. At the onset of labor, all women should be questioned thoroughly about symptoms of genital herpes, including prodromal symptoms , and all women should be examined thoroughly for herpetic lesions. Women without symptoms or signs of genital herpes or its prodrome can deliver vaginally. Although cesarean delivery does not eliminate the risk for HSV transmission to the neonate , women with recurrent genital herpetic lesions at the onset of labor should have a cesarean delivery to reduce the risk for neonatal HSV infection.
Acyclovir 400 mg orally 3 times/dayORValacyclovir 500 mg orally 2 times/day
When To Talk With A Doctor
Herpes isnt curable, but it can be treated with antiviral medications. These medications can reduce the severity of an outbreak.
If you suspect you have herpes, make an appointment with a doctor. Its also a good idea to talk with your doctor about a herpes screening if:
- your current or previous sexual partner has herpes
- youre planning to have sex with a new partner
- you had a risky sexual encounter
If youve already been diagnosed with herpes and youre currently experiencing an outbreak, the outbreak might go away without causing complications and without treatment.
However, its wise to make an appointment with your doctor if:
- the outbreak is particularly painful or unbearable
- youre experiencing symptoms of other STIs
- youre experiencing frequent, severe outbreaks
If youre sexually active, its a good idea to have regular STI screenings. You can book appointments for STI screenings with your doctors office. You could also try a local clinic, certain pharmacies, or Planned Parenthood.
Read Also: Best Way To Test For Genital Herpes
Use Of Aciclovir In Pregnancy Just Before Birth
If you have been infected with the herpes virus and you experience recurrent outbreaks of genital herpes, your doctor or consultant may suggest using Aciclovir in tablet form in the four weeks prior to delivery to prevent the recurrence of genital herpes.
This is so that you dont pass on the viral infection to your baby during delivery.
How Can I Prevent Transmitting Herpes
Although latex condoms can reduce the risk of transmitting most STIs by 98 percent, condoms dont prevent herpes transmission. This is because not all herpes sores occur in areas that are covered by a condom.
If youre experiencing an active outbreak, you can
- avoiding sexual activity until symptoms go away
- washing your hands thoroughly and applying medication with cotton swabs to reduce contact with sores
Taking a daily antiviral herpes medication can also help prevent transmission, shorten outbreaks, and manage symptoms.
Also Check: How To Cure Herpes Zoster
What Can A Person Or Community Do To Prevent The Spread Of Herpes Ii
Avoidance of sexual contact with symptomatic individuals is an immediate, but only partial answer because herpes virus may be shed while the infected individual remains asymptomatic. Cesarean section is often recommended when primary or recurrent herpes II lesions occur in late pregnancy.
Sexual relations should be approached responsibly.
- Limit the number of your sex partners.
- Use a male or female condom.
- If you think you are infected, avoid any sexual contact and visit the local STD clinic, a hospital or your doctor.