Suffering From Herpes Type 2 Outbreaks
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What About Chlamydia The Most Common Std
Chlamydia is caused by bacteria, whereas herpes is caused by a virus. This is why chlamydia is easily treated and cured with antibiotics. However, many people have chlamydia and dont know it because they dont have any symptoms. Thats why people who are at higher risk of chlamydia, including sexually active young women and men who have sex with other men, are advised to get a test for chlamydia every year.
If you dont treat chlamydia, it can increase the chances of both men and women getting or giving HIV and AIDS, according to Medline Plus. Untreated chlamydia can also cause serious pelvic inflammatory disease in women, which can lead to infertility, and in men it can spread to the testicles and the tube that carries sperm, causing inflammation.
Screening for chlamydia is usually done by taking a urine sample or a swab from your genitals. Results of these tests are usually found quickly. Different testing methods are used for infections of the rectum and throat, and these take more time.
While the only way to completely avoid getting chlamydia or herpes is to not have sex, you can reduce your chances of getting both by being in a long-term, mutually monogamous relationship with a partner who is not infected with an STD and by using latex condoms every time you have sex.
Treating A First Outbreak Of Herpes
A first outbreak of genital herpes can cause a long illness with severe genital sores and can also affect the nervous system. Even if your first episode of herpes is mild, you may have severe or prolonged symptoms later. For this reason, the Centers for Disease Control and Prevention recommends that everyone who has a first episode of genital herpes take antiviral drugs.
Almost everyone who has one episode of genital herpes caused by HSV-2 also has later breakouts of sores. Later episodes are less common if your case of genital herpes is due to an HSV-1 infection.
The frequency of genital herpes outbreaks slows down over time in many people.
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What Are The Signs Of Herpes In Children
The herpes virus can be spread to babies and children if they are kissed by someone that is infected and has active cold sores. Although rare, it is also possible to spread herpes to a child or infant by touch if a person touches their cold sore and then touches the baby or child.
Precautions can be taken to protect infants and other children from getting the virus. Avoid kissing children if you have a cold sore and ask other people not to as well. Wash your hands frequently if you have a cold sore and you are around children.
Can You Cure Herpes
Unfortunately, theres no cure for herpes. The virus stays inactive in your body and activates from time to time to cause outbreaks, months or even years after youre first infected. This is when you get symptoms. Antiviral medication for herpes can only help control the outbreaks or suppress the virus.
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Protecting Your Partner And Preventing Herpes Transmission
Research shows that the single greatest fear is the fear of transmission to partners, says Dr. Handsfield.
The main ways to avoid transmitting herpes are:
- Learn to recognize how you feel when an outbreak is on the way, and stop having sex immediately.
- Dont have sex during active outbreaks.
- Always use condoms but dont rely on them during outbreaks. They dont completely cover infectious areas.
- Only after all sores have scabbed over and healed should you have sex again.
- Avoid touching your herpes sores, because you can spread them to other places on your body that way. Whenever you touch a sore, wash your hands immediately.
- Dont kiss people or have sex if you have a cold sore.
- Tell potential partners about having herpes before having sex with them, even though it may be hard.
- Ask your doctor about taking antiviral drugs regularly.
What Treatment Is Available For Genital Herpes
Though genital herpes is not curable, it can be managed. Your physician may prescribe an antiviral medication, including acyclovir, valacyclovir, and famciclovir, to use during an outbreak. Over-the-counter pain medication can also be used to soothe symptoms. Your physician can provide advice on how to prevent transmission of the virus to sexual partners along with suggestions about how to discuss the topic of genital herpes openly.
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Who Is At Risk For Developing Herpes Simplex Infections
Anyone can contract HSV, regardless of age. If youre exposed to HSV, youre likely to contract the virus.
Remember, HSV is very common. But because its often asymptomatic, plenty of people living with the virus never have an episode or realize theyve contracted HSV.
You may have a higher chance of contracting the virus if you:
- have a sexual partner who lives with HSV
- were assigned female at birth . suggests more AFAB folks than people assigned male at birth develop HSV, but this could also mean AFAB folks are more likely to experience symptoms.
- are immunocompromised
Some older research suggests HSV-1 antibodies may offer AFAB folks some protection against contracting HSV-2. Still, many people living with one type of the virus do contract the other type later on. You wont contract the same type of the virus again, though, since it remains dormant in your body once you acquire it.
You may have a slightly higher chance of contracting genital HSV if you have sex without using condoms or other barrier methods. Keep in mind, though, that condoms and other barrier methods wont always cover the infection site, since sores can appear on the buttocks or inner thighs.
What Other Information Should I Know
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to acyclovir.
Do not let anyone else take or use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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What Stands Out About Yale Medicines Approach To Genital Herpes
As an academic medical center, Yale Medicine provides a wide range of treatment options for patients. Our doctors are expert at diagnosing and treating difficult cases and helping manage the condition for people at risk, such as pregnant women. Our doctors have access to the most advanced technology for diagnosing herpes and other medical conditions.Also, our researchers continue to look for new information about the herpes virus.
How Do Dermatologists Treat Herpes Simplex
There is no cure for herpes simplex. The good news is that sores often clear without treatment. Many people choose to treat herpes simplex because treatment can relieve symptoms and shorten an outbreak.
Most people are treated with an antiviral medicine. An antiviral cream or ointment can relieve the burning, itching, or tingling. An antiviral medicine that is oral or intravenous can shorten an outbreak of herpes.
Prescription antiviral medicines approved for the treatment of both types of herpes simplex include:
Taken daily, these medicines can lessen the severity and frequency of outbreaks. They also can help prevent infected people from spreading the virus.
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How Does Genital Herpes Spread
Herpes can be spread when an infected person has lesions blisters and open sores on their body or when you do not have any symptoms. Taking antiviral medicine can help you reduce the risk of spreading genital herpes to your sexual partners. You can also:
- Inform your sexual partner that you have genital herpes.
- Use a condom every time you have sex.
- Refrain from having sex when you have symptoms.
- Abstain from performing oral sex if you have blisters or open sores around your mouth.
Is Herpes Simplex Related To Herpes Zoster
Herpes simplex and the varicella-zoster virus are related, but they arent the same. VZV causes chickenpox and shingles.
Like HSV-1 and HSV-2, shingles can cause a painful, blistering rash. The shingles rash usually shows up on the back, side, abdomen , neck and face. It is often only on half of your body, following the pattern of your nerves. See your healthcare provider if you have a new rash and suspect you may have shingles.
A note from Cleveland Clinic
Herpes simplex is a virus. Once you have herpes, its a lifelong condition. A herpes infection can lead to outbreaks , but youll also have times when you have no symptoms. The main sign of herpes is sores that appear on the infected skin. Some people choose not to treat herpes, especially if symptoms are mild. Others take antiviral medications to reduce the severity and frequency of outbreaks.
Last reviewed by a Cleveland Clinic medical professional on 05/17/2022.
References
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Treatment For Genital Herpes
There are three antiviral medications that are FDA-approved for the treatment of genital herpes:
- Acyclovir: The oldest antiviral medication for herpes is acyclovir. It has been available since 1982 in a topical form and sold since 1985 in pill form. Acyclovir has been shown to be safe in persons who have used it continuously for as long as 10 years.
- Valacyclovir: A newer drug, valacyclovir, actually uses acyclovir as its active ingredient. This medication delivers acyclovir more efficiently so that the body absorbs much of the drug, which has the advantage of taking the medication fewer times during the day.
- Famciclovir: Famciclovir uses penciclovir as its active ingredient to stop HSV from replicating. Like valacyclovir, it is well absorbed, persists for a longer time in the body, and can be taken less frequently than acyclovir.
Antiviral medication is commonly prescribed for patients having a first episode of genital herpes, but they can be used for recurrent episodes as well. There are two kinds of treatment regimens: episodic therapy and suppressive therapy.
When Is Preventive Treatment Considered
Some people have outbreaks of genital herpes very often or experience especially severe symptoms. Then it may be a good idea to take antiviral medication for a longer time including during symptom-free phases. The goal is to prevent further outbreaks and to keep the symptoms from becoming so severe. Also, the antiviral medication reduces the likelihood of infecting others. As preventive treatment, the WHO recommends the following:
- aciclovir: 400 mg two times per day,
- famciclovir: 250 mg two times per day or
- valaciclovir: 500 mg once per day.
Research shows that preventive treatment can considerably lower the risk of further outbreaks. The people participating had four or more herpes outbreaks per year before the start of the studies, and then took an antiviral medication or a fake treatment for up to one year. A comprehensive analysis of the study results shows that
- 96 out of 100 people who took a placebo had at least one further outbreak of genital herpes.
- 46 out of 100 people who were given antiviral medication had at least one further outbreak of genital herpes.
In other words, the medication prevented further outbreaks in 50 out of 100 people within one year.
People with very frequent herpes outbreaks also benefited from preventive treatment: In one study involving people with very frequent outbreaks, the medication lowered the number of episodes in one year from 11 to 2.
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How Should This Medicine Be Used
Acyclovir comes as a tablet, a capsule, and a suspension to take by mouth. It also comes as a delayed-release buccal tablet to apply to the upper gum of the mouth. The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin. When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months. The delayed-release buccal tablet is usually applied with a dry finger as a one-time dose within 1 hour after itching, redness, burning or tingling cold sore symptoms begin but before the cold sore appears. Take or use acyclovir at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take or use acyclovir exactly as directed. Do not take or use more or less of it or take it more often or for a longer time than prescribed by your doctor.
Do not chew, crush, suck, or swallow the delayed-release buccal tablets. Drink plenty of liquids, if you have a dry mouth while using the delayed-release buccal tablets.
Avoid The Following While You Are Using Acyclovir Buccal Delayed
- Do not chew gum, touch, or press the buccal tablet after it has been applied.
- Do not wear upper dentures.
- Do not brush your teeth until it dissolves. If your teeth need to be cleaned while the tablet is in place, rinse the mouth gently.
Shake the suspension well before each use to mix the medication evenly.
Your symptoms should improve during your treatment with acyclovir. Call your doctor if your symptoms do not improve or if they get worse.
Take or use acyclovir until you finish the prescription, even if you feel better. If you stop taking acyclovir too soon or skip doses, your infection may not be completely treated or may become more difficult to treat. The delayed-release buccal tablet is applied as a one-time dose.
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What Happens Once You Have Hsv
Once a person becomes infected with a herpes virus, the virus never leaves the body. After the first outbreak, the virus moves from the skin cells to nerve cells. The virus stays in the nerve cells forever. But it usually just stays there. In this stage, the virus is said to be dormant, or asleep. But it can become active again.
Some things that can trigger the virus are:
Is There A Cure For Herpes Simplex
There is no cure for herpes simplex. Once you have the virus, its a lifelong infection.
What is the outlook for people with herpes simplex?
For many people, the first herpes outbreak is the most severe. Many outbreaks are less frequent and milder after the first year of infection. Some people may have only one outbreak and never have another again.
Herpes infection doesnt usually pose a serious health risk. The risk of a health complication due to herpes is higher in infants and if you have HIV/AIDS, cancer or an organ transplant.
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The Virus And Pathogenesis
HSV is a double-stranded DNA virus that may enter the host through abraded skin or intact mucous membranes.1 Epithelial cells are the initial targets. Once infected, these cells die, releasing clear fluid intradermally to form vesicles and merging with other cells to create multinucleated giant cells.
Retrograde transport through adjacent neural tissue to sensory ganglia leads to lifelong latent infection.1 Reactivation of the virus is triggered by local or systemic stimuli such as immunodeficiency, trauma, fever, menstruation, ultraviolet light and sexual intercourse.13 Although emotional stress is assumed to trigger HSV recurrence, recent research fails to show a definite causative role.4 Once reactivated, the virus is transported by the neuron back to the epithelium, where more replication occurs, and another outbreak ensues.
HSV exists as two separate types, labeled 1 and 2, which have affinities for different body sites.2 Ninety percent of infections caused by HSV-2 are genital, and 90 percent of those caused by HSV-1 are oral the reason for this division is unknown.5 In addition, oral HSV-1 infection recurs more frequently than oral HSV-2, and genital HSV-2 recurs more often than genital HSV-1.
What Can You Expect When Visiting A Doctor For Ocular Herpes Diagnosis
Ocular or eye herpes can be often misdiagnosed during early stages. Documenting your symptoms and when they occurred can help you receive a more accurate diagnosis. You should bring these notes to your doctors appointment and be prepared to answer questions about your medical history.
In most cases during your diagnosis appointment you can expect the following 3 things:
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How Do Herpes Drugs Work
Sometimes drugs behave very well. They do what they are supposed to so, and do it well, maybe even without side effects . We are fortunate to have one of these that works against a very common infectionherpes simplex virus .
There are two versions of the virus. HSV-1 is the type that causes cold sores, and HSV-2, which causes genital herpes . The two viral types are similar enough that they both respond well to the same drugacyclovir . The way that acyclovir works is a textbook example of an antiviral drug in actionshutting down an essential step that brings viral replication to a halt. The essential step that is shut down is the prevention of the formation of a phosphate ester bonda key step in the manufacture of viral DNA. No DNA, no more viruses. Pretty cool stuff.
Acyclovir inhibits DNA polymerasethe enzyme that is responsible for assembling the individual components of DNA into a very large chain, DNA itself. The drug is classified as a chain terminator, for reasons that will become apparent later on.
On the left is the structure of guanine one of the four bases that exist in DNAbound to deoxyribose , the sugar that makes up DNA . On the right is the structure of acyclovir. The similarity of the two structures is evident, but so are the differences . The difference between the two is shown in red 1t is obvious that acyclovir contains only a small portion of ribose.
Like I said, pretty cool stuff.
Notes: