Oral Antiviral Medication For Herpes
Most people who get herpes will not experience bothersome symptoms, but for those that do there is effective oral antiviral medication. It stops the herpes from multiplying but does not clear the virus from the body. The most common brand used in New Zealand is valaciclovir. It is safe and works effectively for both Type 1 and Type 2 herpes simplex.
Is There Anything I Can Do To Relieve The Symptoms Myself
In some women, genital herpes blisters cause pain when urinating . Many of them find it soothing to pee while sitting in warm, shallow water . You can do this using special tubs that fit into toilet bowls. They are available at a reasonable price, for instance from pharmacies or on the internet. It’s best not to use soaps or bath additives because they can irritate the affected area even more. Other things you can do to avoid irritating it further include wearing loose-fitting clothes and underwear made out of fabrics that have a smooth surface.
Painkillers such as ibuprofen are an option if the blisters become very painful.
Topical antiviral treatments such as creams or ointments don’t provide any relief, but they can increase the risk of viral resistance. Experts advise against using topical treatments for genital herpes.
Risks Of Herpes During Pregnancy
The major risk associated with herpes and pregnancy is neonatal herpes infections. These infections of the newborn are rare, but can be quite serious or even fatal. The biggest risk for neonatal herpes occurs for people who are newly infected during pregnancyparticularly near the time of delivery.
Cesarean section is recommended instead of vaginal delivery for people who have genital symptoms at the time of delivery. It is also recommended for people who are having prodromal symptoms that signal a likely outbreak. C-section has been shown to significantly reduce the risk of herpes transmission to the infant.
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When To Talk With A Doctor
Herpes isnt curable, but it can be treated with antiviral medications. These medications can reduce the severity of an outbreak.
If you suspect you have herpes, make an appointment with a doctor. Its also a good idea to talk with your doctor about a herpes screening if:
- your current or previous sexual partner has herpes
- youre planning to have sex with a new partner
- you had a risky sexual encounter
If youve already been diagnosed with herpes and youre currently experiencing an outbreak, the outbreak might go away without causing complications and without treatment.
However, its wise to make an appointment with your doctor if:
- the outbreak is particularly painful or unbearable
- youre experiencing symptoms of other STIs
- youre experiencing frequent, severe outbreaks
If youre sexually active, its a good idea to have regular STI screenings. You can book appointments for STI screenings with your doctors office. You could also try a local clinic, certain pharmacies, or Planned Parenthood.
When To Get Tested
Consult a doctor about any of the following symptoms:
- tingling or itching around the genitals
- pain when peeing
- unusual vaginal discharge
The World Health Organization describes the risk of the herpes virus passing to a newborn during childbirth. Although this is rare, people who are pregnant and have herpes should let their doctors know.
Using a condom or another barrier method of protection during sex reduces the risk of the virus transmitting. It is also a good idea to avoid sharing sex toys with someone who has herpes.
Several online companies offer STI testing kits, including:
- EverlyWell: This company sells tests for chlamydia, gonorrhea, syphilis, herpes, and HIV.
- LetsGetChecked: This company sells tests for several common STIs, and it provides prescriptions at no extra cost if a test result is positive.
- PriortitySTD: This company returns results within 3 days.
Anyone with a positive test result should contact a healthcare professional.
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What Is Valtrex Used For
The Food and Drug Administration approved Valtrex for the following indications:
- Genital herpes, usually caused by herpes simplex virus 2
- Prevention of transmission of HSV
- Suppression of HSV
- Suppression of HSV for people who are immunosuppressed due to human immunodeficiency virus
- Shingles, which is caused by reactivation of varicella zoster and produces a painful rash
The dosing of Valtrex differs for children and adults and is based on weight for the treatment of chicken pox. Valtrex is used short term for the treatment of chicken pox, shingles, and cold sores.
It can also be used for the short-term treatment of genital herpes or long term to suppress the virus and prevent transmission to a partner. However, it is important to remember that Valtrex will not cure your herpes infection completely.
Verywell / Dennis Madamba
Side Effects And Follow
Side effects with these herpes drugs are considered mild, and health experts believe these drugs are safe in the long term. Acyclovir is the oldest of the three, and its safety has been documented in people taking suppressive therapy for several years.
People taking suppressive therapy should see their doctor at least once a year to decide if they should continue. You may find taking the pills every day to be inconvenient, the drugs may not work for you, or you may naturally have fewer outbreaks as time goes on. Your doctor can help you make treatment choices to suit your needs.
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How Effective Is Herpes Medication
Antiviral herpes medication will not cure oral or genital herpes infections. However, suppressive therapy significantly ameliorates its symptoms. The Centers for Disease Control and Prevention determined that this treatment can reduce genital herpes outbreaks by 70%-80% in patients that frequently experience them.
When And How Are Later Outbreaks Treated
Later outbreaks with only mild symptoms dont necessarily need to be treated. The blisters can then simply heal on their own.
But antiviral medication can also shorten the duration of later outbreaks by an average of about two days. If you decide to have treatment, its important to start it within the first 24 hours of the outbreak ideally, as soon as you notice the first symptoms. So its a good idea to always have a few tablets at home or to take them with you when you travel so they are ready to use. You can get a prescription from your doctor.
In later outbreaks you can take them for a shorter time. The WHO recommends the following:
- aciclovir: 400 mg three times per day or 800 mg two times per day for five days, or 800 mg three times per day for two days,
- famciclovir: 250 mg two times per day for five days, or
- valaciclovir: 500 mg two times per day for three days.
A different dose and treatment duration may be a good idea for people who have immune system disorders, such as an HIV infection.
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What Medications Are Similar
There are several antiviral medications that are similar to Valtrex but do not have identical approved indications. These include:
- Sitavig and Zovirax : This medication is available as a tablet or a liquid to be swallowed. It is also available in an injectable form to be used for severe HSV infections, including HSV encephalitis . It is also available as a cream for the treatment of cold sores.
- Famvir : This is available as a tablet for the treatment of cold sores, genital herpes, and shingles.
Many other antiviral medications are used for treating different infections. For example, Epivir and Viread are used to treat HIV. Baraclude is used to treat hepatitis B.
Education Is An Integral Part Of Herpes Treatment
If you have genital herpes, its important for you to get educated about herpes and have the opportunity to ask questions in a supportive environment.
Becoming informed will help you learn to cope with the illness. It will also help you prevent sexual transmission of the illness, or transmission to an infant during a pregnancy.
Herpes has a tremendous psychosocial overlay. But knowledge about it and understanding about how well it can be managed can reduce that, says Handsfield.
Your doctor may be able to provide you with all the information you need, or you may choose to seek counseling from a mental health professional or at a clinic that specializes in sexual health, such as Planned Parenthood.
If you have a regular sexual partner, that person should also have the chance to learn about herpes and ask any questions they may have about it.
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Valacyclovir Dosage For Genital Herpes
If you have genital herpes, youll understand how stressful an outbreak can be. People infected with genital herpes can experience four to five outbreaks of the virus per year, making it vital to have medication like valacyclovir on hand in the event you notice herpes lesions developing.
Like oral herpes, valacyclovir is highly effective at treating genital herpes and speeding up the healing process.
Genital herpes occurs in two phases. After being infected with the virus, most people will have an initial outbreak a powerful outbreak of the virus that can result in severe symptoms. After this, genital herpes presents itself in recurring outbreaks every few months.
The typical dose of valacyclovir used to treat an initial outbreak of genital herpes is 1,000 mg taken two times per day. This twice-daily 1,000 mg dosage usually continues over 10 days as the herpes outbreak retreats and the lesions close, scab and heal.
During a very severe initial outbreak of genital herpes, your doctor might recommend taking valacyclovir over a longer period.
For recurring genital herpes, the typical dosage of valacyclovir is 500 mg taken twice daily for three days.
As with cold sores, valacyclovir is most effective at treating genital herpes when its taken as early as possible during an outbreak. Taken early, consistently and at the right dose, use of valacyclovir can make dealing with a difficult genital herpes outbreak more manageable.
What Is Acyclovir And How Does It Work
Acyclovir is approved by the Food and Drug Administration as a prescription drug that is commonly used as a topical, injectable, and oral treatment for genital herpes and cold sores. Herpes refers to a group of viruses that cause a variety of herpes infections including genital herpes, shingles, chicken pox , cold sores, and encephalitis . Herpes viral infections are very common. Genital herpes refers to a sexually transmitted disease that any sexually active person can contract and transmit.
Shingles and chicken pox are common skin conditions. Shingles and chicken pox are skin infections which are both caused by the herpes virus. They are not caused by the same virus that causes cold sores or genital herpes.
Many people who suffer from shingles or chicken pox infection will experience symptoms such as a rash, often with pain, which is treatable with this drug.
Genital herpes is an STD caused by two types of viruses: herpes simplex type 1 and herpes simplex type 2. Most people with genital herpes do not know they have it. Still, symptoms often appear days to weeks after exposure. Symptoms of genital herpes generally include:
- Flu-like symptoms such as fever, body aches, or swollen glands
- Blisters, sores, or rash in the genital area with or without pain, itching, tingling
- Blisters that pop open, causing painful sores.
Acyclovir may also help treat pain associated with an outbreak of genital herpes after the sores heal.
Acyclovir is the generic equivalent of Zovirax.
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Treatment Of Common Cutaneous Herpes Simplex Virus Infections
DAVID H. EMMERT, M.D., Lancaster General Hospital, Lancaster, Pennsylvania
Am Fam Physician. 2000 Mar 15 61:1697-1704.
Herpes simplex virus infection is increasingly common in the United States. New antiviral medications have expanded treatment options for the two most common cutaneous manifestations, orolabial and genital herpes. Acyclovir therapy remains an effective and often less expensive option. Famciclovir and valacyclovir offer improved oral bioavailability and convenient oral dosing schedules but are more expensive than acyclovir. Patients who have six or more recurrences of genital herpes per year can be treated with one of the following regimens: acyclovir, 400 mg twice daily valacyclovir, 1 g daily or famciclovir, 250 mg twice daily. These regimens are effective in suppressing 70 to 80 percent of symptomatic recurrences. Episodic treatment of recurrent genital herpes is of questionable benefit, but it may be helpful in appropriately selected patients. There is little evidence indicating benefit from treatment of recurrent orolabial herpes, which tends to be mild and infrequent.
Treatment Of Primary Infection
Antiviral therapy is recommended for an initial genital herpes outbreak, especially if the patient has systemic symptoms or is immunocompromised.2 Oral acyclovir is effective in reducing symptoms1 . Intravenous administration may be required in immunocompromised patients and those with severe disseminated infection.1 Topical acyclovir reduces the duration of viral shedding and the length of time before all lesions become crusted, but this treatment is much less effective than oral or intravenous acyclovir.1
Effect of Acyclovir Treatment on Primary Genital Herpes
| Symptom/sign |
|---|
|
Time until all lesions are crusted |
|
Time until all lesions are healed |
*Dosage = 200 mg five times daily for 10 days, given within six days of lesion onset.
Information from Mertz GJ, Critchlow CW, Benedetti J, Reichman RC, Dolin R, Connor J. Double-blind placebo-controlled trial of oral acyclovir in first-episode genital herpes simplex virus infection. JAMA 1984 252:114751.
Effect of Acyclovir Treatment on Primary Genital Herpes
| Symptom/sign |
|---|
|
Time until all lesions are crusted |
|
Time until all lesions are healed |
*Dosage = 200 mg five times daily for 10 days, given within six days of lesion onset.
Information from Mertz GJ, Critchlow CW, Benedetti J, Reichman RC, Dolin R, Connor J. Double-blind placebo-controlled trial of oral acyclovir in first-episode genital herpes simplex virus infection. JAMA 1984 252:114751.
Famciclovir is not FDA-labeled for this indication.
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How Do Other Antivirals Work
Antivirals are medications used in the treatment and prevention of various types of viral infections. Other antivirals are medications that are not categorized into any specific classes of antivirals. Most of the other antivirals block viral replication by interfering with DNA polymerase, an enzymevital for DNA synthesis and viral replication.
Some of the other antivirals are active drugs that directly take effect, while some are prodrugs, which release the active form of the drug after being metabolized. Other antivirals include the following:
- Acyclovir: Acyclovir is an active drug effective against herpes simplex virus 1 and 2 that cause genital and oral herpes, and varicella-zoster virus which causes chickenpox and shingles. Acyclovir gets incorporated into the viral DNA, inhibits DNA polymerase, and terminates the DNA chain to prevent viral replication.
- Brincidofovir: Brincidofovir is a prodrug approved for treating human smallpox, a disease caused by the variola virus. Although smallpox has been eradicated with vaccination, concerns that the variola virus can be used as a bioweapon remain.
- Brincidofovir penetrates cells and releases cidofovir which is metabolized to produce cidofovir diphosphate, the active drug that selectively inhibits orthopoxvirus DNA polymerase-mediated viral DNA synthesis and reduces the rate of viral DNA synthesis.
- Herpes zoster infection , which is caused by reactivation of VZV
I Sometimes Get Twinges And Pains Around My Buttocks Or Down One Leg What Does This Mean
Occasionally, herpes simplex virus can cause burning skin sensations, deep aches or sudden twinges in the genital area. When they occur in the thighs or buttocks, they are sometimes compared to sciatica. These symptoms are called prodromes or prodromal symptoms. They are a sign that the virus is trying to reactivate and there may be virus on the skin surface. Sometimes sores will follow, but very often your immune response overcomes the virus before visible signs appear. For email version or posted version of more information on treating genital herpes, select tips to prevent recurrences on the subscription form.
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How Is Genital Herpes Treated
Genital herpes is an infection caused by the herpes simplex virus . The virus causes an outbreak of blisters which are common herpes symptoms. Treatment is with antiviral medication to help prevent and control outbreaks.
If youre unsure if you have herpes, you can take a genital herpes test at home.
There are 3 main types of treatment for genital herpes:
Aciclovir tablets are used for outbreaks of genital herpes or cold sores to treat the symptoms. They can also be used to prevent outbreaks from happening if you get them often. How much you take and how long you take them for can vary depending on what youre using it for whether youre using it to treat an outbreak or to prevent future outbreaks.
Valaciclovir tablets are known as a pro-drug, which means your body converts it into aciclovir after you take them. Like aciclovir tablets, they can be used to treat symptoms or to prevent outbreaks.
A doctor may prescribe famciclovir tablets if you find that aciclovir or valaciclovir havent worked for you.
Serious Side Effects Of Valtrex
Although its rare, Valtrex can cause more serious side effects that may require medical attention, including:
- Low blood cell counts
- Painful periods for women
If youre taking Valtrex and have any of these symptoms, you should contact your doctor for medical advice as soon as possible.
If you have any signs of an allergic reaction like difficulty breathing, hives, or swelling of the face, mouth, or throat, you should seek immediate emergency medical treatment.
Other serious side effects that could potentially occur when taking Valtrex include:
- Inflammation of the liver
- A serious blood disorder called thrombotic thrombocytopenic purpura/hemolytic uremic syndrome
Some patients are more susceptible to these serious side effects than others. Consult your healthcare provider to find out if youre at risk.
These side effects are very rare. Antiviral medicines are effective at treating viral infections, but after long-term use, they can eventually weaken the immune system by affecting immune cells. This is typically only an issue for seniors and people with weakened immune systems. Even though its not typically taken for long periods of time, if your doctor does want you to take it long term, then thats okay. Some studies have even shown that the long-term use of Valtrex is well-tolerated for healthy individuals.
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